IVF at 50 – Best IVF Clinics and Countries

From the age of around 30, egg quality, the main determinant of achieving pregnancy, begins to decline and by the time a woman reaches 50, it is near impossible to get pregnant naturally. Whilst many countries and treatment providers impose a strict legal age limit for those women seeking fertility treatments, IVF at 50 is not an impossibility. This article examines the pros and cons of IVF for older mothers including success rates, pregnancy risks, and treatment options.

IVF over 50 – is it possible?

Scientific and medical advancements attempt to make the impossible achievable and it is no different with fertility treatments. Being 50 and pregnant is certainly not common but it is naturally possible in an exceptionally small number of cases and fertility experts, with increasingly sophisticated and successful fertility treatments at their disposal mean that IVF at 50 or older is no longer impossible. There are obviously a number of pregnancy risks which come with IVF with older mothers which we discuss later in this article but for many women who have not found a partner or delayed a pregnancy because of career motives, it is now possible to find a fertility clinic who will offer you IVF treatment.

Dr Emma Maria Adsuar, gynaecologist at UR Vistahermosa explains:

The age of maternity is increasing worldwide. Historically, it has been defined as more than 35 years old, but in recent years it has changed. Nowadays, advanced maternal age is defined as more than 35-38 years old. Extreme advanced maternal age means more than 48 years old. As of now, there is an egg donation technique available for a 48-year-old woman who can get pregnant.

Can a 50-year-old woman get pregnant naturally?

Every woman is born with a finite number of eggs and through the natural processes of ovulation and ageing this number steadily decreases over time which in turn impacts our fertility. The ability of the ovaries to maintain their reproductive potential is also affected by genetic abnormalities, injury or some medical treatments. Therefore, the ability of a 50-year-old patient to achieve a natural pregnancy is reliant on a number of factors including general health conditions. It is, however, possible for a healthy 50-year-old patient who hasn’t reached menopause to get pregnant naturally, in principle.

IVF over 50 – everything you need to know

For many, the benefits of having a child at a more advanced age outweigh any associated health problems. At 50, you may well be more financially stable, you might have achieved your personal and career goals and be ready psychologically and practically to start a family. Equally, you may have met a partner later in life. The reasons for considering a later pregnancy are numerous.

What are those pregnancy risks associated with advanced age? Well, to mention a few, there are risks of high blood pressure leading to preeclampsia, diabetes and a raised incidence of miscarriage. In addition, the later in life you have a baby, there is a higher risk of them experiencing birth defects, learning disabilities, low birth weight and chromosome related conditions like Down syndrome.

A natural pregnancy in your 50s is therefore possible in a very small number of cases depending upon your health (physical and psychological) but there are both positive and negative considerations to take into account.

IVF at 50 with own eggs

Achieving a successful pregnancy with IVF at 50 with own eggs is extremely challenging; in fact, many professionals would argue that a conservative success rate would stand at around 1%. Whilst age is a very important contributory factor to success rates it should be remembered that each patient is different. Success will not only depend upon the individual health of the patient but the experience and skill of the medical and scientific teams responsible for the treatment as well as the technology employed. If you are considering the possibility of IVF at 50 you should seek independent advice from a fertility specialist and undertake health screenings before committing to treatment.

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IVF at 50 with own eggs – best clinics and costs

In some countries, there is a strict legal age limit for patients receiving fertility treatment. For instance, in Greece, the law states that IVF for older women is limited to those up until the age of 54 and women aged 50-54 require additional qualification. Other countries offer the same guidance but this is not backed by specific legislation. In the UK, for instance, private clinics will consider treatment on an individual basis but are very explicit in explaining that success rates using your own eggs are very low at the age of 50.

There are a limited number of countries that will treat women aged 50 and over using their own eggs and these include North Cyprus, Latvia, and the United States. Within these countries, the official line is that whilst it is not advisable to offer treatments to all women over 50 there is some flexibility within the system which allows clinics to make clinical decisions based on an individual patient basis.

The cost of treatment is not age-dependent per se but many clinics will recommend additional health screenings and hormone testing for patients in their 50s to rule out potential health problems associated with IVF for older mothers. These additional tests come at a price and bearing in mind the low success rates for IVF for women over 50 using their own eggs it is likely that you will require a number of cycles. The result, therefore, is IVF treatment for those women over 50 wanting to use their own eggs can be an expensive process.

As a rule of thumb those countries mentioned in this section offer IVF treatments that are lower in price than the average offered in Central Europe or the UK with the exception of the United States where prices are considerably higher.

IVF over 50 with donor eggs

Many professional bodies including the American Society for Reproductive Medicine (ASRM) recommend that clinics should only treat ‘healthy’ women over the age of 50. However what constitutes ‘healthy’ appears to be up for discussion (does it take into account, BMI, cholesterol levels, high blood pressure, diabetes, or hypertension for instance) so clinics appear to have to use their discretion on an individual basis.

IVF donor egg success rates are much higher than treatments using the eggs of patients in their 50s. Medical and scientific consensus suggests that rates jump from an average of 1% when using own eggs to approximately 60% when donor eggs are used.

As IVF treatment for those in their 50s is not strictly (legally) prohibited in the majority of countries there is the possibility of accessing donor treatment in a number of countries as long as the clinics are satisfied with your physical and mental health – some clinics, for instance, will recommend counselling to sit alongside any donor treatment you seek.

Dr Esther Marban, fertility expert at Clinica Tambre explains:

The main indications for egg donation include premature ovarian failure, where the patient no longer menstruates, making egg donation the ideal solution. Additionally, many patients with failed IVF treatments, often linked to low-quality and low-quantity eggs, are primarily caused by age-related factors. Other cases may involve problems that pre-implantation genetic screening cannot diagnose, making egg donation a viable option.

The advice for any woman over the age of 50 who wants to undergo IVF with donor eggs is to seek advice early and where possible obtain a general health check prior to contacting clinics.

Related reading

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• Donor egg IVF success rates – the truth clinics don’t tell you
• The Good Fight – IVF and egg donation in Spain
• IVF Double Donation: Using Donor Eggs and Sperm

IVF over 50 with donor eggs – best clinics and costs

There are a number of countries that explicitly say that they will consider treating women over 50 when using donor eggs. These countries include Greece, North Cyprus, Latvia, Russia and the United States whilst in others individual clinics will have their own policies and practices like the UK. It is recommended therefore that you spend some time seeking independent advice or contacting clinics in a number of countries to evaluate your options.

Actual treatment costs associated with the use of donor eggs are the same regardless of age but you may be required to undergo additional health screenings or tests to rule out any health problems.

Many types of treatment attract various ‘guarantee programmes’ and ‘refund’’ schemes which offer financial help with the cost. However, these schemes operate strict eligibility criteria and it is very likely that due to the lower success rates achieved by IVF for older patients these will be inaccessible.

IVF over 50 with donor embryos or/and sperm

There are both embryo and sperm donation programmes offered across the majority of European countries with certain exceptions such as Germany, Norway, Switzerland and Turkey. Access is dependent upon country legislation, donor availability, the extent of consent originally given by the donor and individual clinic policy.

If you are considering this route for treatment you will also need to be mindful of different countries’ attitudes to treatment based on a patient’s relationship status. For instance, in countries such as the UK, Greece, Spain, Sweden, Denmark, and North Cyprus this is not relevant but others like Poland and the Czech Republic do not offer embryo donation programmes to single women or to couples in the same sex relationship, regardless of age.

Success rates for treatments using donor embryos or/and sperm are amongst the highest available. The caveat based on age however still applies – when searching for treatment options check to see what criteria clinics assess whether patients are sufficiently ‘healthy’ to undergo treatment if they are in their 50s.

IVF over 50 with donor embryos – best clinics and costs

Prices for donor embryo treatment vary considerably so do your research if you are considering this route. It is certainly an option in a number of countries where there is some flexibility regarding treatment eligibility. Remember also that some countries offer donor anonymity whilst others do not (including Austria, Croatia, Finland, Malta and the U.K.).

As stated previously, as a 50-year-old patient you won’t be able to access many ‘pregnancy guarantee’ programmes as these are primarily aimed at younger patients. Many individual clinics, however, do offer bespoke treatment packages so it is an idea to check before you commit to a specific treatment pathway.

Costs for donor embryo treatment in Europe vary between 1,400 Euros (e.g., Czech Republic) to countries like Spain where treatments can cost up to 3,500 Euros.

IVF over 50 best clinics

IVF at 50 – summary

The number of women looking to have a baby at the age of 50 and older is on the increase. According to data released by the Office For National Statistics in the UK the number of patients who were aged 50 plus quadrupled in the first two decades of this century.

There may be obstacles that older IVF patients have to overcome but these are not insurmountable. There are many fertility clinics offering treatment options available to older patients in different countries. Whilst IVF at 50 with own eggs is extremely difficult to succeed the use of donor eggs or donor embryos significantly increases pregnancy rates.

50 and pregnant is no longer unachievable – a route to parenthood in your 50s is now a realistic option.

IVF at 50 – FAQ

In vitro fertilization (IVF) is a complex and evolving field of reproductive medicine. As more individuals seek to start families later in life, questions about the feasibility and implications of IVF at older ages, such as 50, have become increasingly common. This FAQ aims to address some of the most frequently asked questions and provide clear, concise information on this topic.

Can a 50-year-old woman get pregnant with own eggs?

Yes, but the chances are extremely slim. Chances will depend on a number of factors including general health and her ability to produce viable eggs. Age is important for predicting success rates but it is not the sole factor in achieving a pregnancy at the age of 50.

What are IVF success rates in 50-year-old women?

A common assumption used is that there is a 1% chance of success for women undergoing IVF at 50 using their own eggs which rises to around 60% when having treatment with donor egg.

What are the best IVF clinics in Europe and the world for over 50?

There is not a specific league table for clinics specializing in treating older patients. The best clinics are those which consistently offer good success rates across different age ranges and treatments. Prior to committing to a treatment plan and clinic, however, ask about their specific experience in treating older patients and their success rates with this group.

Can a menopausal woman have IVF?

The short answer is yes. Once you finally have your last period you can’t get pregnant naturally but you can undergo IVF with donated eggs or eggs you have personally donated and that have been frozen.

What is the maximum age for IVF in the UK?

There is no specific legal upper age limit for women patients although the NHS will generally only fund treatment for patients aged up to 42. Private clinics have the discretion to treat older patients as long as they are deemed healthy to undergo IVF treatment.

Is 49 too old for IVF?

49 is not too old for IVF but your treatment options and destinations might be restricted. Potential success rates will be reduced if you want IVF treatment using your own eggs but the use of donor eggs or embryo will significantly increase your chances of getting pregnant.

What are the risks of IVF at 50?

One of the primary concerns is the increased risk of pregnancy-related complications. Women over 50 are more susceptible to conditions such as preeclampsia, gestational diabetes, and hypertension during pregnancy. These complications can pose serious health risks to both the mother and the baby, necessitating close monitoring and careful management by healthcare professionals throughout the pregnancy.

Another major risk is the higher likelihood of miscarriage. As women age, the quality of their eggs declines, which can lead to chromosomal abnormalities in embryos. Although donor eggs are often used for older women undergoing IVF, which can mitigate some of these risks, the recipient’s age still plays a crucial role in the overall success and safety of the pregnancy. Additionally, older women face a higher risk of preterm birth and low birth weight babies. Premature infants often require specialized medical care and can face long-term health challenges. The chances of requiring a cesarean section also increase with age, which carries its own set of risks and longer recovery times.

There are also broader health considerations to keep in mind. At 50, many women may have underlying health conditions such as cardiovascular disease or diabetes, which can complicate both the IVF process and the pregnancy. It’s crucial for women in this age group to undergo thorough medical evaluations to assess their overall health and ability to carry a pregnancy to term safely.

Psychological and emotional factors are also important. Pregnancy and parenthood at an older age can be physically and emotionally demanding. Prospective parents should consider the long-term implications, including the physical ability to care for a young child as they age. Moreover, there are ethical and social considerations. Some people may face societal judgments or concerns about the long-term welfare of the child, given the parents’ age. These aspects should be carefully weighed and discussed with family and healthcare providers.

What lifestyle changes should I make before starting IVF at 50?

First and foremost, maintaining a healthy diet is crucial. Focus on a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats. Nutrients such as folic acid, vitamin D, iron, and calcium are particularly important for women preparing for pregnancy. Consider consulting with a nutritionist who can help create a personalized meal plan that meets your specific nutritional needs.

Regular physical activity is also vital. Exercise helps maintain a healthy weight, reduces stress, and improves overall physical fitness, which is beneficial for pregnancy. Aim for moderate-intensity activities such as walking, swimming, or yoga. These exercises are gentle on the body yet effective in maintaining fitness. However, avoid overly strenuous activities, and always consult your doctor before starting any new exercise regimen.

Reducing stress is another essential factor. High stress levels can negatively impact fertility and overall health. Techniques such as mindfulness, meditation, and acupuncture have been shown to reduce stress and improve overall well-being. Engaging in hobbies, spending time with loved ones, and ensuring you get adequate rest are also important for maintaining a calm and positive state of mind.

It’s important to manage any chronic health conditions effectively. Conditions such as hypertension, diabetes, and thyroid disorders should be well-controlled before starting IVF. Regular check-ups with your healthcare provider are essential to ensure these conditions are managed properly and to discuss any medications you are taking that might affect your fertility or pregnancy.

How do I prepare mentally and emotionally for IVF at 50?

Professional counseling can be very beneficial. A therapist specializing in fertility issues can help you navigate the emotional complexities of IVF, providing strategies to cope with stress, anxiety, and any fears you may have. Counseling can also strengthen your relationship with your partner, ensuring you both stay connected and supportive.

Engaging in mindfulness and stress reduction techniques can improve your emotional well-being. Practices like meditation, yoga, and deep breathing exercises can help calm your mind and reduce stress, enhancing your emotional resilience.

Educating yourself about the IVF process can reduce anxiety. The more you know about the steps involved, the timeline, and potential outcomes, the more empowered and prepared you will feel. Maintaining a positive mindset is also important. Focus on the reasons you’re pursuing IVF and the potential joy it could bring. Engage in activities that keep you optimistic and balanced, acknowledging and processing negative emotions while fostering hope. Taking care of your physical health through regular exercise, a healthy diet, and adequate sleep can also positively influence your mental and emotional state. A strong, healthy body can improve your overall outlook and readiness for the journey ahead.

What are the chances of multiple births with IVF at 50?

The likelihood of multiple births with IVF at the age of 50 is generally higher than with natural conception, primarily due to the practice of transferring multiple embryos to increase the chances of achieving a successful pregnancy. However, this probability can vary based on several factors, such as the number of embryos transferred and the specific protocols of the fertility clinic.

Women at the age of 50 often use donor eggs because their own eggs have usually decreased in quality and quantity. Donor eggs from younger women tend to be more viable, which can enhance the success rates of IVF. When more than one embryo is transferred, the likelihood of twins or higher-order multiples increases. Clinics often recommend transferring multiple embryos for older patients to improve the chances of implantation and pregnancy. However the number of embryos to transfer can be restricted by a country law or national recommendations and guidelines.

It’s crucial to recognize that multiple pregnancies carry higher risks than singleton pregnancies, especially for women over 50. These risks can include preterm birth, low birth weight, gestational diabetes, preeclampsia, and complications during delivery. To mitigate these risks, many clinics now favor elective single embryo transfer (eSET) policies when high-quality embryos are available, thereby reducing the chances of multiple births.

Recent advancements in reproductive technology and improved embryo selection techniques, such as preimplantation genetic testing (PGT), allow for the transfer of fewer embryos while maintaining high success rates. This strategy helps minimize the likelihood of multiple births and their associated risks.

Please note, the decision regarding the number of embryos to transfer should be made in close consultation with your fertility specialist. They will take into account your overall health, the quality of the embryos, and your personal preferences to develop a tailored treatment plan that aims to balance the success of achieving pregnancy with the risks of multiple births.

Can I have a healthy pregnancy and baby at 50 through IVF?

Yes, it is possible to have a healthy pregnancy and baby at 50 through IVF, particularly when using donor eggs from younger women. Donor eggs can significantly improve the chances of a successful pregnancy because they are more likely to be healthy and viable.

However, pregnancy at this age carries higher risks, including gestational diabetes, preeclampsia, and complications during delivery. Close monitoring by healthcare professionals is essential to manage these risks effectively.

With proper medical care and a healthy lifestyle, many women at 50 can achieve a successful and healthy pregnancy and birth through IVF. Always consult with your fertility specialist to discuss your specific circumstances and any potential risks.

What are the long-term health implications for women who undergo IVF at 50?

Undergoing IVF at 50 can have several long-term health implications. Women in this age group are at a higher risk for pregnancy-related complications such as gestational diabetes, hypertension, and preeclampsia, which can have lasting health effects. Additionally, the physical demands of pregnancy and childbirth can be more challenging for older women, potentially leading to a longer recovery period.

Post-pregnancy, there may be an increased risk of cardiovascular issues and other age-related health conditions exacerbated by the physical strain of pregnancy. Regular follow-up with healthcare providers is essential to monitor and manage any long-term health impacts effectively. Always consult with your doctor to understand the specific risks and to develop a plan for maintaining your health.

Can I get IVF at 55?

Yes, IVF is possible at 55, but it almost always involves using donor eggs. Many IVF clinics may have age restrictions, and success rates decrease as age increases, but some clinics do offer treatments to women in their mid-50s under certain health conditions.

Can a 57-year-old woman get pregnant naturally?

It is extremely rare for a 57-year-old woman to get pregnant naturally. By this age, natural fertility has typically ceased due to menopause, and pregnancy would generally require the use of donor eggs and IVF.

How successful is IVF at 50?

The success rate of IVF at 50 with your own eggs is very low, but using donor eggs significantly increases the chances of success, often resulting in a 50-60% success rate per cycle.

What is the oldest age for IVF?

The oldest age for IVF depends on the country and clinic, but it is generally around 50-55 years old with donor eggs. Some clinics may offer IVF to women in their 60s under special circumstances.

Which country is best for IVF?

The best country for IVF can depend on factors such as success rates, legal restrictions, and the quality of care. Countries like Spain, Greece, and the Czech Republic are popular for their high standards of fertility treatments, especially for older women or those needing donor eggs.

What is the maximum age for IVF in Spain?

In Spain, there isn’t a strict legal age limit for IVF, but most Spanish IVF clinics set their own limits, typically around 50-52 years old. This is due to the health risks associated with pregnancy at an advanced age.

What is the maximum age for IVF in Greece?

In Greece, the legal age limit for IVF is 54 years old. This applies to all women, including those using donor eggs. Several well-established Greek clinics offer IVF treatments up to this age, ensuring safe and regulated care for women pursuing fertility treatments.

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